SiPhox Health offers at-home minimally invasive blood tests combined with wearable device data (optional) to provide a comprehensive snapshot of your health and lifestyle.

Read about each health category and the associated biomarkers below.

Blood Biomarkers

Inflammation[1]

Inflammation plays a key role in a healthy immune response. However, during aging, chronic, low-grade inflammation – called inflammaging – develops, which contributes to the pathogenesis of many age-related diseases. Inflammation is also associated with depression and other chronic illnesses.

• hs-CRP
• Homocysteine (high range)
• 25-(OH) Vitamin D
• Ferritin (high range)

Metabolic Fitness[2]

Metabolic fitness is the condition of a robust and healthy set of cellular mechanisms that produce energy from our food and environment to power every process in the human body. Poor Metabolic Fitness is associated with worse brain function, energy, memory, mood, skin health, fertility, and like inflammation, puts us at greater risk for chronic diseases.

• Hemoglobin A1c
• Fasting Insulin
• Trig:HDL Ratio
• 25-(OH) Vitamin D

Balance[3]

Your Balance score includes hormonal and nutritional markers. Balance means maintaining the appropriate amount (not too high or too low) of hormones and critical vitamins/minerals. This is key to keeping our internal environment running at its peak.

• Testosterone (Male) Estradiol (Female)
• Testosterone:Cortisol Ratio (Male)
• DHEA-S (Male)
• Folate
• Ferritin (low range)
• Homocysteine (low range)

Cardiovascular[4]

Your Cardiovascular score includes markers that have the potential to lead to heart disease. Poor Cardiovascular health puts individuals at risk for shortened lifespan and decreased quality of life. Tracking these markers allows you to optimize your diet and lifestyle to stay healthier, longer.

• HDL
• LDL
• Total Cholesterol:HDL Ratio
• Triglycerides
• ApoA1
• ApoB
• ApoB:ApoA Ratio

Wearable Device Data

Activity[5]

Your weekly activity average includes number of steps and minutes spent engaging in different zones of exercise intensity.

• Daily Steps
• Minutes Spent in Medium Intensity Activities
• Minutes Spent in High Intensity Activities

Sleep[6]

Your sleep score reflects your average sleep duration and quality.

• Sleep Total Duration
• REM Sleep
• Deep Sleep
• Sleep Efficiency

Heart Efficiency[7]

Heart Efficiency is a measure of your current heart health and athleticism. Increased heart efficiency is correlated with increased lifespan.

• Resting Heart Rate
• Average Heart Rate Variability

Ready to start testing?

Send My SiPhox Health Kit

References[−]

The post What We Measure appeared first on mTelehealth.

Vitamin D is a fat-soluble vitamin that is essential to many of the body’s processes. Whether supporting immune, musculoskeletal, or brain health, Vitamin D is definitely a valuable player in maintaining overall health and wellness.

The History of Vitamin D

But to really understand Vitamin D, we need to go back to the early 1600s when rickets in children and osteomalacia in adults were first described. Coinciding with the Industrial Revolution, a combination of indoor occupations, smog, and decreased dietary calcium intake may have contributed to Vitamin D deficiency. Without sufficient Vitamin D, calcium is not properly absorbed, and bones become soft, weak, and deformed.

Centuries later in Great Britain, Sir Edward Mellanby, a biochemist, was concerned with the incidence of rickets in the United Kingdom and hypothesized that the disease was caused by a dietary deficiency. To test this, he fed dogs a strict diet of oatmeal (the main diet of Scottish folk who had the highest incidence of rickets at the time) and kept them away from sunlight. Once the dogs developed rickets, he noticed that they could be cured with cod liver oil. To determine whether it was Vitamin A or another vitamin that was responsible, Professor Elmer McCollum of Johns Hopkins University decided to conduct an experiment of his own. By destroying Vitamin A from the cod liver oil, McCollum identified that a new vitamin, which they called Vitamin D, was the true component responsible for curing the disease.

Eventually, dietary supplementation and fortification of food and infant formula led to a decrease in nutritional rickets. However, Vitamin D deficiency prevails. Social and cultural shifts including preferences for fair skin, a sedentary lifestyle, health concerns over skin cancer, time constraints, and many other factors have led to decreased ultraviolet B (UVB) exposure.

Who is susceptible to deficiency?

A few characteristics can make a person more susceptible to deficiency. Living in regions with low sunlight such as northern latitudes, especially during the winter months, can limit the amount of natural Vitamin D that your body synthesizes, even if you spend time outside. People with darker skin tones are prone to being deficient because melanin inhibits Vitamin D synthesis. As people age, the skin becomes less efficient at synthesizing Vitamin D. Additionally, since Vitamin D is a fat-soluble vitamin, people who are overweight or obese may have Vitamin D sequestered in fat cells, which results in lower circulating Vitamin D concentrations. Ultimately, geographic location, melanin levels, age, and obesity status, in addition to diet, disorders, and medication, could all potentially impact Vitamin D availability.

So if Vitamin D is so important, how can we prevent deficiency?

Chances are, when you think about Vitamin D, you think of sunlight. Spending about 10-30 minutes in the sun a few times a week, exposing your skin to the UVB rays, can help your body naturally synthesize Vitamin D. The amount of time needed varies based on factors such as your skin type, geographic location, and UV index. If you live in an area without as much sunlight, you can try a UV lamp. Diet is another way to obtain Vitamin D. Fatty fish such as salmon, mackerel, and trout are excellent sources. Egg yolks and mushrooms also contain some, but many foods nowadays such as milk, orange juice, breakfast cereals, and yogurt are often fortified with Vitamin D. Supplements are a convenient, accessible option if you have dietary restrictions or limited sun exposure. If you are concerned about your Vitamin D levels or have specific health conditions, it is advisable to consult with a healthcare professional. They can assess your Vitamin D status and recommend appropriate treatment options based on your individual needs.

Bibliography

Deluca HF. History of the discovery of vitamin D and its active metabolites. Bonekey Rep. 2014 Jan 8;3:479.

“Vitamin D.” Mayo Clinic, Mayo Foundation for Medical Education and Research, 10 Aug. 2023.

“Vitamin D.” The Nutrition Source, 7 Mar. 2023.

Wheeler BJ, Snoddy AME, Munns C, Simm P, Siafarikas A, Jefferies C. A Brief History of Nutritional Rickets. Front Endocrinol (Lausanne). 2019 Nov 14;10:795.

The post The Untold Story of Vitamin D appeared first on mTelehealth.

What is apolipoprotein B?

Apolipoproteins are proteins that carry lipids in our blood. Apolipoprotein B (ApoB) is insoluble, which means that it cannot exist freely in the plasma. It is always part of a lipoprotein particle. These particles are important for the transportation of “bad” lipids between various tissues. The role of ApoB molecules is to maintain the structure of the atherogenic (artery-clogging) lipoproteins, to enable the transport of lipids in the plasma, and to control lipoprotein metabolism. Every atherogenic particle contains one molecule of apoB, so concentrations of apoB are a direct measure of the total number of lipoproteins causing atherosclerosis (plaque-filled artery). The measurement of apoB is an estimate of low-density lipoprotein (LDL) particle number because more than 90% of ApoB in plasma is associated with LDL.

What is LDL?

The higher the number of LDL particles, the higher the risk of atherosclerosis. If there are high levels of LDL particles in the blood over a long period of time, they may cross the arterial wall in greater amounts than usual. In this way, the LDL particles are exposed to changes, such as oxidation. These oxidized LDL particles induce a local inflammatory and immune response. It leads to the proliferation of the smooth muscle cells in the arterial wall and the formation of the fibrous cap of the atherosclerotic plaque. The plaque is unstable and can rupture easily, which may lead to vascular stenosis. It means that the lumen of the vein is narrowed, so the blood cannot reach the target organs adequately. If the lumen is totally blocked, it may lead to a stroke.

Artery-clogging lipoproteins can cause the build-up of plaques and consequently limit blood flow. This may lead to heart attacks, strokes, and other cardiovascular diseases.

LDL vs ApoB as Biomarkers

Both ApoB levels and LDL levels are used to predict the risk of atherosclerosis. Usually, they correlate with each other. However, in some individuals with normal or even low LDL concentrations, atherosclerotic events occur. ApoB levels are a far better predictor of atherosclerotic risk than LDL concentrations because the cholesterol content in the particles can vary widely between individuals. Small, dense LDL particles contain less cholesterol than larger ones. It means that the apoB levels are high, but the LDL concentration can be normal or even low. It is common in patients with diabetes and metabolic syndrome. Studies have shown that cardiovascular risk is more closely associated with the number of particles than with the mass of cholesterol. Taking this into account, ApoB is widely regarded as a more accurate measurement for identifying individuals with an increased risk of atherosclerosis than LDL.

Sources

Mehta, A., & Shapiro, M.D. (2022). Apolipoproteins in vascular biology and atherosclerotic disease. Nature Reviews Cardiology, 19, 168-179. https://doi.org/10.1038/s41569-021-00613-5

Langlois, M.R., & Sniderman, A.D. (2020). Non-HDL Cholesterol or apoB: Which to Prefer as a Target for the Prevention of Atherosclerotic Cardiovascular Disease?. Current Cardiology Reports, 22, 67. https://doi.org/10.1007/s11886-020-01323-z

The post How Are Lipoprotein Particles Assessed? (ApoB vs LDL) appeared first on mTelehealth.

What is the yearly physical blood panel? Why do doctors order those specific tests?

• Complete blood count (CBC) — Measures different cells and parts of your blood, which can help detect infections, anemia, blood clots, immune system disorders and blood cancers.
• Chemistry panel (complete metabolic panel) — Measures the levels of different chemicals in the blood, which can provide detailed information about your bones, muscles and other organs.
  • Calcium, one of the body’s most important minerals. Calcium is essential for proper functioning of your nerves, muscles, and heart.
  • Sodium, potassium, carbon dioxide, and chloride. These are electrolytes, electrically charged minerals that help control the amount of fluids and the balance of acids and bases in your body.
  • Albumin, a protein made in the liver.
  • Total protein, which measures the total amount of protein in the blood.
  • ALP (alkaline phosphatase), ALT (alanine transaminase), and AST (aspartate aminotransferase). These are different enzymes made by the liver.
  • Bilirubin, a waste product made by the liver.
  • BUN (blood urea nitrogen) and creatinine, waste products removed from your blood by your kidneys.
• Lipid panel (cholesterol test) — Measures the different proteins which carry both good and bad cholesterol in the blood, which can help determine your risk for heart disease, heart attack or stroke.
  • Lipids include cholesterol, triglycerides, high-density lipoprotein (HDL), and low-density lipoprotein (LDL).
• Blood sugar screen — Measures your blood sugar levels, which can help in the process of diagnosing diabetes.
  • HbA1c, and fasting glucose
• Thyroid health
  • TSH, Free T3, Free T4
• Micronutrients
  • B12, Vitamin D, minerals

• What essential things we don’t measure
  • Kidney function tests BUN, Creatinine
  • Liver function tests ALT, AST
  • CBC
  • Some Micronutrients
• Is this test a replacement for a yearly physical?
  • No, this is an adjuvant to a yearly physical
  • It’s still important to get your yearly physical in order to monitor liver function, kidney function, and a more comprehensive micronutrient and metabolic overview.
• Why we chose our specific panel
  • The most informative biomarkers that provide a complete picture of your health when combined with a yearly physical
  • The biomarkers we test would be very expensive if done through a lab service like LabCorp
  • We measure things that change rapidly and require testing more than once a year
  • We test things that are rarely tested on the yearly physical test

The post What We Don’t Measure appeared first on mTelehealth.

Increase Energy Levels

Feelings of exhaustion and constant fatigue are becoming more prevalent than ever in adults today, preventing than from engaging in daily activities. Several factors can contribute to low energy levels, including inadequate sleep, sedentary lifestyles, and underlying health issues. Certain biomarkers are linked to these factors, making it essential to track them to isolate the root of issues. Especially in the midst of COVID-19, low energy levels can indicate chronic fatigue syndrome (CFS). CFS greatly impedes productivity and quality of life while reducing life expectancy by over 20 years[1].

Low Energy Can Be Traced to a Variety of Causes

Several factors can contribute to low energy levels, including inadequate sleep, poor nutrition, a sedentary lifestyle, chronic stress, and underlying medical conditions such as anemia, thyroid disorders, or depression. Understanding the causes of low energy is crucial for identifying appropriate strategies to improve overall well-being and restore vitality.

What is chronic fatigue syndrome?

Chronic Fatigue Syndrome (CFS), also known as myalgic encephalomyelitis (ME), is a complex and debilitating condition characterized by persistent and unexplained fatigue that lasts for at least six months and is not improved by rest. CFS is often paired with disturbances to sleep, weakened cognitive function, and reduced physical ability. It is believed to be caused by genetic, immune, hormonal, and environmental factors, making it especially important to measure biomarkers that may influence this condition.

Biomarkers Shed Light on Causes of Low Energy

Due to the high variety of factors that influence energy levels and the fact that these many of causes do not manifest themselves visibly, it is difficult to pinpoint what is causing your fatigue. However, measuring biomarkers provides an accurate reason for low energy to inform further treatment or lifestyle changes, and can allow for preventative measures to stop energy levels from even dropping in the first place.

START YOUR JOURNEY

Which biomarkers are closely connected to low energy levels?

Insulin

Proper insulin function maintains stable blood sugar for sustained energy. Imbalances manifest as insulin resistance, impairing glucose uptake and causing low energy. Hypoglycemia arises from excess insulin or insufficient glucose due to skipped meals, excessive insulin use, medical conditions, leading to fatigue and decreased energy levels.

Vitamin D

Vitamin D is crucial for overall health and energy levels. It supports cellular energy metabolism, muscle function, and immune function. Deficiency can lead to fatigue and increased vulnerability to illness. Adequate Vitamin D through sunlight, diet, or supplementation is essential for optimal energy and well-being.

Ferritin

Ferritin is the protein that stores iron. Iron deficiency, indicated by low ferritin levels, can cause fatigue. Iron is vital for oxygen transport and energy production in cells. Insufficient iron can hamper energy generation, resulting in tiredness and decreased energy. Addressing iron deficiency can alleviate fatigue and enhance energy levels.

Testosterone

Testosterone is essential for energy levels in both men and women. Adequate levels maintain energy, vitality, and motivation, supporting metabolic processes and muscle function. Low testosterone can lead to decreased energy, fatigue, reduced stamina, and lack of motivation, impacting quality of life. High testosterone can lead to irritability.

START YOUR JOURNEY

HERE’S THE DEAL

Why choose Dr. Miltie, Powered by SiPhox?

The lowest cost per biomarker testing, at-home sample collection,
interactive reports, and actionable insights.

At-Home Testing

No more driving to clinics. No more waiting in lines. The sample collection kit lets you collect your sample using only a few drops of blood.

Extremely Affordable

Blood testing is expensive. But it shouldn’t be. Meet Dr. Miltie, the lowest-cost per-biomarker test on the market.

Measure Progress

Users tell us that regular testing is key to reaching their goals. Whether you want to lose weight or have more energy—we have your back!

Actionable Insights

Personalized insights sets you up for success. Paired with your favorite wearables, our system creates insights to improve each biomarker.

COMPREHENSIVE TEST KIT

17 Included Biomarkers

Our at-home test kit contains the biomarkers you need to provide you with the best overall snapshot of your health.

Base

Cardiovascular Health

Hormonal & Nutritional Balance

Hormone+

Inflammation

Metabolic Fitness

TG:HDL Ratio

Vitamin D

Triglycerides

Total Cholesterol

TC:HDL Ratio

Testosterone:Cortisol

Testosterone

LDL

Insulin

Homocysteine

HDL

hs-CRP

ApoB:ApoA1

Cortisol

DHEA-S

Estradiol

Ferritin

TSH

FSH

HbA1c

ApoB

ApoA1

A FEW DROPS OF BLOOD

Is a few drops of blood really enough?

That’s right! A few drops of blood is all we need to test 17 biomarkers. Sounds too good to be true? Far from it…

Our sample collection card, the ADX100¹, is an alternative collection method, similar to an SST tube. Red blood cells are separated without a centrifuge, enabling the laboratory to perform tests on dry blood.

Are results accurate? Yes! We process samples in a 3rd party CLIA-certified lab. The test results have been cross-validated against standard finger prick and venous draws.

SELF SAMPLE-COLLECTION

Can I really collect my own sample?

Each kit contains a sample collection card, three adjustable lancets, band-aids, sterile gauze, an alcohol pad, and instructions.

Drawing your blood sounds scary at first. Especially if it’s your first time doing it. We’ve taken the time to make the instructions as easy to follow as possible.

Not only that, every customer can schedule a live one-on-one session with our certified phlebotomist for FREE (a person trained in collecting blood samples).

PERSONALIZED REPORTS

Ok, my results are in. What now?

This is the best part! After processing your sample, we create a complete report for each of your 17 biomarkers.

You can then access your reports from your personal reports dashboard. Each report comes with an easy-to-understand graph and personalized insights you can use to improve each biomarker.

The dashboard lets you connect your favorite wearables to make your reports even more insightful. Improved sleep and activity scores are highly correlated with improved hormonal balance and lower inflammation in our user base.

CORRELATE YOUR DATA

Include Your Wearable

Frequently Asked Questions

If your question is not found below, feel free to email us your question at: support@DrMiltie.com

Is the SiPhox Health blood test kit equivalent to standard labs?

How are you able to offer the lowest cost per biomarker in the industry?

Which biomarkers are being tested?

Why should I use a wearable with SiPhox Health?

What wearable devices are compatible with SiPhox Health?

How do I view my test results?

What makes SiPhox Health Reports unique?

Can I give my kit away as a gift?

I’m having trouble collecting enough blood for the test, what can I do?

I think I messed up my collection card. What do I do?

What is the Hormone+ Panel?

References

The post How Tracking Biomarkers Can Increase Energy Levels appeared first on mTelehealth.

Heart Health

Regular monitoring of heart health parameters, such as blood pressure, cholesterol levels, and heart rate, can help prevent cardiovascular diseases and promote overall well-being. It empowers individuals to make informed lifestyle choices and seek timely medical intervention if necessary, ultimately contributing to a longer and healthier life.

Measure the Success of Treatment

Medical professionals will typically prescribe medication to treat heart health issues, or to simply improve overall heart health. Monitoring biomarkers relevant to cardiovascular health allows you to verify the success of supplements and medicines in your routine. Testing regularly, at your own pace, will help you see how your biomarkers change as you implement healthy changes.

Early Detection

Detecting signs of serious health issues before they become major has consistently been hailed as a surefire way to curb disease risk.[1] By reading your biomarkers semi-regularly, you can take massive strides in facilitating the early detection of potential cardiovascular issues, enabling timely intervention and treatment before they progress to more serious conditions.

Monitoring Fitness

Monitoring heart health is especially crucial for fitness enthusiasts and athletes. Regular monitoring of heart health biomarkers can provide valuable insights into the efficiency and effectiveness of cardiovascular performance during exercise. Tracking biomarkers such as heart rate, blood pressure, and cholesterol levels can help optimize training intensity, assess cardiovascular endurance, and identify potential cardiovascular risks associated with intense physical activity. Whether it is through a wearable or at home blood test, it is becoming increasingly easy to monitor several critical fitness-related biomarkers without a visit to the doctor.[2]

START YOUR JOURNEY

Which Biomarkers are closely related to heart health?

ApoB

It has been established for almost 20 years that ApoB is a better predictor of heart disease than LDL cholesterol. Since heart disease is the leading cause of death in the US, addressing ApoB and making cardioprotective lifestyle modifications is critical to living healthier longer.[3, 4]

Triglycerides

High triglycerides are directly linked to higher risk of heart disease and stroke. High levels of this biomarkers and its implication can be successfully reversed by exercising regularly, losing weight if overweight, avoiding refined carbohydrates, limiting alcohol and avoiding stress.[5]

Cholesterol

High amounts of cholesterol inhibit the flow of blood in your body, which can have serious implications. It is often the result of lifestyle, but high cholesterol can also be inherited. [6]

APoA1

Higher levels of ApoA1 are associated with a reduced risk of cardiovascular diseases, including coronary artery disease and heart attacks.[7] Additionally, ApoA1 possesses anti-inflammatory and antioxidant properties, further contributing to cardiovascular protection.

START YOUR JOURNEY

HERE’S THE DEAL

Why choose Dr. Miltie, Powered by SiPhox?

The lowest cost per biomarker testing, at-home sample collection,
interactive reports, and actionable insights.

At-Home Testing

No more driving to clinics. No more waiting in lines. The sample collection kit lets you collect your sample using only a few drops of blood.

Extremely Affordable

Blood testing is expensive. But it shouldn’t be. Meet Dr. Miltie, the lowest-cost per-biomarker test on the market.

Measure Progress

Users tell us that regular testing is key to reaching their goals. Whether you want to lose weight or have more energy—we have your back!

Actionable Insights

Personalized insights sets you up for success. Paired with your favorite wearables, our system creates insights to improve each biomarker.

COMPREHENSIVE TEST KIT

17 Included Biomarkers

Our at-home test kit contains the biomarkers you need to provide you with the best overall snapshot of your health.

Base

Cardiovascular Health

Hormonal & Nutritional Balance

Hormone+

Inflammation

Metabolic Fitness

TG:HDL Ratio

Vitamin D

Triglycerides

Total Cholesterol

TC:HDL Ratio

Testosterone:Cortisol

Testosterone

LDL

Insulin

Homocysteine

HDL

hs-CRP

ApoB:ApoA1

Cortisol

DHEA-S

Estradiol

Ferritin

TSH

FSH

HbA1c

ApoB

ApoA1

A FEW DROPS OF BLOOD

Is a few drops of blood really enough?

That’s right! A few drops of blood is all we need to test 17 biomarkers. Sounds too good to be true? Far from it…

Our sample collection card, the ADX100¹, is an alternative collection method, similar to an SST tube. Red blood cells are separated without a centrifuge, enabling the laboratory to perform tests on dry blood.

Are results accurate? Yes! We process samples in a 3rd party CLIA-certified lab. The test results have been cross-validated against standard finger prick and venous draws.

SELF SAMPLE-COLLECTION

Can I really collect my own sample?

Each kit contains a sample collection card, three adjustable lancets, band-aids, sterile gauze, an alcohol pad, and instructions.

Drawing your blood sounds scary at first. Especially if it’s your first time doing it. We’ve taken the time to make the instructions as easy to follow as possible.

Not only that, every customer can schedule a live one-on-one session with our certified phlebotomist for FREE (a person trained in collecting blood samples).

PERSONALIZED REPORTS

Ok, my results are in. What now?

This is the best part! After processing your sample, we create a complete report for each of your 17 biomarkers.

You can then access your reports from your personal reports dashboard. Each report comes with an easy-to-understand graph and personalized insights you can use to improve each biomarker.

The dashboard lets you connect your favorite wearables to make your reports even more insightful. Improved sleep and activity scores are highly correlated with improved hormonal balance and lower inflammation in our user base.

CORRELATE YOUR DATA

Include Your Wearable

Frequently Asked Questions

If your question is not found below, feel free to email us your question at: support@DrMiltie.com

Is the SiPhox Health blood test kit equivalent to standard labs?

How are you able to offer the lowest cost per biomarker in the industry?

Which biomarkers are being tested?

Why should I use a wearable with SiPhox Health?

What wearable devices are compatible with SiPhox Health?

How do I view my test results?

What makes SiPhox Health Reports unique?

Can I give my kit away as a gift?

I’m having trouble collecting enough blood for the test, what can I do?

I think I messed up my collection card. What do I do?

What is the Hormone+ Panel?

References

The post Why should you be tracking your heart health markers? appeared first on mTelehealth.

Reduce Brain Fog

Brain fog is a cognitive symptom characterized by difficulties with focus, memory, and mental clarity. It can manifest as a feeling of mental sluggishness, impacting daily productivity and overall cognitive functioning. Brain fog can serve as an indicator of an underlying illness, a result of hormonal changes, or even a long-run side effect of a past ailment, so it is important to measure biomarkers to differentiate between causes. In recent times, brain fog has been a common symptom for individuals who contracted COVID-19, with 32% of patients experiencing brain fog months after sickness.¹

Brain Fog Can Occur Due to Multiple Factors

Brain fog is a symptom of a plethora of conditions, lifestyle choices, and medications. Causes can range from chronic stress to chronic illnesses such as fibromyalgia. Hormonal imbalances and side effects from medications that impact cognitive function, such as antidepressants, are other common sources of brain fog. Additionally, chronic illnesses often cite brain fog as a symptom, with conditions like fibromyalgia and chronic fatigue syndrome impairing mental clarity.

What is the link between Covid-19 and brain-fog?

One of COVID-19’s most common long-term symptoms is brain fog, often experienced months after the initial infection and regardless of the severity of the case. This phenomenon occurs due to the body’s inflammatory and immune response to the virus, resulting in inflammation of the central nervous system and the creation of antibodies that mistakenly target healthy brain tissue. In addition, the virus and its vascular damage inhibit blood flow to the brain, culminating in problems with memory and cognitive function.

Brain Fog May Sound Vague, but It Can Have Debilitating Effects

Brain fog can significantly impact daily activities. It can result in reduced productivity, difficulties with concentration and problem-solving, and challenges in maintaining optimal cognitive functioning. Brain fog can make it harder to complete tasks, impact decision-making abilities, and hinder overall cognitive performance. It may also lead to feelings of frustration, fatigue, and decreased motivation.

START YOUR JOURNEY

Which biomarkers are closely connected to brain fog?

Cortisol

If your cortisol levels—along with serotonin—are out of balance, you may find yourself emotional and sluggish. This imbalance can also cause trouble sleeping and can affect mental clarity. Lack of sleep can also lead to increased cortisol levels, causing a vicious cycle.

TSH

TSH, released by the pituitary gland, stimulates the thyroid gland to produce thyroid hormones (T4 and T3) that regulate brain cell metabolism. Abnormal TSH levels, like high TSH in hypothyroidism or low TSH in hyperthyroidism, can disrupt thyroid hormone balance. Hypothyroidism, with low thyroid hormone levels, is linked to cognitive impairments and brain fog due to inadequate thyroid hormone supply to the brain.

hs-CRP

High-sensitivity C-reactive protein (hsCRP) is a biomarker of systemic inflammation in the body. Inflammation can affect various organs, including the brain, and has been associated with cognitive dysfunction and brain fog. Elevated levels of hsCRP indicate increased inflammation, which may contribute to the development or exacerbation of brain fog symptoms.

Hormonal Imbalance

Changes in sex hormone levels can also contribute to brain fog. In individuals with low testosterone levels, brain fog may occur due to its impact on cognitive function. Similarly, imbalances in estradiol levels can also affect cognitive function. In women, fluctuations in estradiol during the menstrual cycle or during menopause have been associated with cognitive changes, including brain fog.

START YOUR JOURNEY

HERE’S THE DEAL

Why choose Dr. Miltie, Powered by SiPhox?

The lowest cost per biomarker testing, at-home sample collection,
interactive reports, and actionable insights.

At-Home Testing

No more driving to clinics. No more waiting in lines. The sample collection kit lets you collect your sample using only a few drops of blood.

Extremely Affordable

Blood testing is expensive. But it shouldn’t be. Meet Dr. Miltie, the lowest-cost per-biomarker test on the market.

Measure Progress

Users tell us that regular testing is key to reaching their goals. Whether you want to lose weight or have more energy—we have your back!

Actionable Insights

Personalized insights sets you up for success. Paired with your favorite wearables, our system creates insights to improve each biomarker.

COMPREHENSIVE TEST KIT

17 Included Biomarkers

Our at-home test kit contains the biomarkers you need to provide you with the best overall snapshot of your health.

Base

Cardiovascular Health

Hormonal & Nutritional Balance

Hormone+

Inflammation

Metabolic Fitness

TG:HDL Ratio

Vitamin D

Triglycerides

Total Cholesterol

TC:HDL Ratio

Testosterone:Cortisol

Testosterone

LDL

Insulin

Homocysteine

HDL

hs-CRP

ApoB:ApoA1

Cortisol

DHEA-S

Estradiol

Ferritin

TSH

FSH

HbA1c

ApoB

ApoA1

A FEW DROPS OF BLOOD

Is a few drops of blood really enough?

That’s right! A few drops of blood is all we need to test 17 biomarkers. Sounds too good to be true? Far from it…

Our sample collection card, the ADX100¹, is an alternative collection method, similar to an SST tube. Red blood cells are separated without a centrifuge, enabling the laboratory to perform tests on dry blood.

Are results accurate? Yes! We process samples in a 3rd party CLIA-certified lab. The test results have been cross-validated against standard finger prick and venous draws.

SELF SAMPLE-COLLECTION

Can I really collect my own sample?

Each kit contains a sample collection card, three adjustable lancets, band-aids, sterile gauze, an alcohol pad, and instructions.

Drawing your blood sounds scary at first. Especially if it’s your first time doing it. We’ve taken the time to make the instructions as easy to follow as possible.

Not only that, every customer can schedule a live one-on-one session with our certified phlebotomist for FREE (a person trained in collecting blood samples).

PERSONALIZED REPORTS

Ok, my results are in. What now?

This is the best part! After processing your sample, we create a complete report for each of your 17 biomarkers.

You can then access your reports from your personal reports dashboard. Each report comes with an easy-to-understand graph and personalized insights you can use to improve each biomarker.

The dashboard lets you connect your favorite wearables to make your reports even more insightful. Improved sleep and activity scores are highly correlated with improved hormonal balance and lower inflammation in our user base.

CORRELATE YOUR DATA

Include Your Wearable

Frequently Asked Questions

If your question is not found below, feel free to email us your question at: support@DrMiltie.com

Is the SiPhox Health blood test kit equivalent to standard labs?

How are you able to offer the lowest cost per biomarker in the industry?

Which biomarkers are being tested?

Why should I use a wearable with SiPhox Health?

What wearable devices are compatible with SiPhox Health?

How do I view my test results?

What makes SiPhox Health Reports unique?

Can I give my kit away as a gift?

I’m having trouble collecting enough blood for the test, what can I do?

I think I messed up my collection card. What do I do?

What is the Hormone+ Panel?

References

The post How Tracking Biomarkers Can Help You Reduce Brain Fog appeared first on mTelehealth.

Huberman on Biohacking your Cortisol

Andrew Huberman is an American neuroscientist and tenured professor in the Department of Neurobiology at the Stanford University School of Medicine. In addition to his scientific research, Andrew Huberman has gained popularity for sharing his knowledge and insights on various platforms, such as podcasts, YouTube, and social media. He is the host of the “Huberman Lab Podcast,” where he discusses neuroscience, health, and human performance. Cortisol is one of the biomarker that Andrew Huberman references frequently in his long-form health optimization episodes on sleep, energy, mood, and hormonal balance. Below are the highlights of Huberman on what role cortisol levels play in your body and how to biohack them.

What is cortisol?

Cortisol is a steroid hormone derived from cholesterol and produced by the adrenal glands, involved in stress response, metabolism, inflammation regulation, blood pressure control, and immune function. Managing cortisol levels is crucial to avoid health issues linked to chronic stress and maintain overall well-being.

In the Huberman Lab Podcast #18, Andrew Huberman explains that cortisol and adrenaline are essential hormones that regulate our energy levels, focus, and immune system function. He emphasizes that these hormones are not inherently good or bad, but rather their regulation is crucial. Huberman states, “They’re terrific when they’re regulated, they are terrible when they’re misregulated.”

What does cortisol do and how does it relate to your circadian rythm?

Cortisol plays several specific roles in the body:
1. Stress response
2. Glucose metabolism
3. Anti-inflammatory properties
4. Blood pressure regulation
5. Immune function modulation

In his podcast, Dr. Andrew Huberman explains that cortisol is a hormone that is released in the morning to wake us up and stimulate movement. He emphasizes that “cortisol is not necessarily a stress hormone, but rather a hormone of energy.”

This is why it’s linked to wakefulness and circadian rythm.

“So the first tool is to make sure that your highest levels of cortisol are first thing in the morning when you wake up. One way or another, every 24 hours, you will get an increase in cortisol. That is non-negotiable. That is written into your genome. That increase in cortisol is there to wake you up and to make you alert.”

Cortisol levels naturally vary throughout the day, following a pattern called the cortisol awakening response (CAR), which is closely related to the circadian rhythm. The circadian rhythm is the body’s internal 24-hour clock that regulates various physiological processes, including sleep, metabolism, and hormone production.

Cortisol levels are typically lowest around midnight and start to increase in the early morning hours before waking. They reach their peak approximately 30 minutes after.

Huberman on Biohacking your Cortisol 3 waking up, which is known as the cortisol awakening response. This peak in cortisol levels helps to jumpstart the body and provide energy for the day. After this peak, cortisol levels gradually decline throughout the day, reaching their lowest levels in the evening, which facilitates relaxation and sleep.

Disruptions to the natural cortisol pattern can negatively impact overall health and wellbeing. Factors such as stress, jet lag, shift work, and exposure to artificial light at night can disrupt the circadian rhythm and cortisol secretion patterns. In the context of biohacking and health optimization, it is essential to maintain a balanced circadian rhythm and cortisol pattern. Strategies include maintaining a consistent sleep-wake schedule, getting exposure to natural sunlight during the day, reducing stress, and avoiding exposure to blue light from electronic devices in the evening.

In his podcast, Dr. Andrew Huberman explains that cortisol is a hormone that is released in the morning to wake us up and stimulate movement. He emphasizes that cortisol is not necessarily a stress hormone, but rather a hormone of energy. According to Dr. Huberman, cortisol and adrenaline are not inherently good or bad, but rather their effects depend on their regulation and timing of release. He suggests that chronic stress can lead to a cascade of stress and negative effects on the body.

Cortisol’s relationship to testosterone and estrogen

Excess Cortisol not only increases stress levels and makes it difficult to sleep, but it can also decrease your sex hormone levels, as Huberman points out:

But seldom is it discussed how sleep actually adjusts things like testosterone and estrogen. And it does it by modifying cortisol. So the molecule cholesterol can be converted into testosterone or estrogen, but there’s a competition whereby the cholesterol will turn into cortisol and not testosterone, or it’ll turn into cortisol and not estrogen if stress levels are too high.

How to measure and track your cortisol

1. Quest Diagnostics:

• Appointment required
• Clinic visit required
• Venous blood draw
• $65
• Number of biomarkers included: 1
• Sleep and activity tracking: Not Included
• 1-5 business days after collection

2. Letsgetchecked:

• At-home kit
• Huberman on Biohacking your Cortisol 5
• Fingerprick sample self-collection (one-size fits all lancets)
• $99 one-time, $69 subscription
• Number of biomarkers included: 1
• Sleep and activity tracking: Not Included
• 2-5 business days after collection

3. Inside Tracker:

• Appointment required
• At-home blood draw visit
• $348
• Number of biomarkers included: 17 including Cortisol
• Sleep and activity tracking: Included, 3 devices supported
• 2-5 business days after collection

4. SiPhox Health Kit:

• At-home kit delivered to your home
• Fingerprick sample self-collection (low-pain, adjustable lancets)
• $295 one-time, $85 subscription
• Number of biomarkers included: 17 including Cortisol
• Sleep and activity tracking: Included, 200 devices supported
• 2-5 business days after collection

Biohacking your cortisol with Huberman

If you measure your cortisol and find that its out of range, don’t worry! There are plenty of hacks to try for regulating and normalizing your cortisol levels.

1. Morning Sunlight

One of the major tools Dr. Huberman recommends is getting sunlight in the morning to regulate cortisol levels. As he puts it,

the best way to stimulate that increase in cortisol at the appropriate time is that very soon after waking within 30 minutes or so after waking, get outside view some sunlight, even if it’s overcast, get outside view some sunlight, no sunglasses.

2. Avoiding blue light at night?

And I should also say avoiding bright lights from artificial sources in the evening, generally 10 PM to 4 AM, but certainly in the evening trying to dim lights in your immediate environment, trying to avoid bright screens, bright artificial lights as much as possible and accessing that deep sleep.

3. Eating carbs

Huberman notes that you can use carbs (judiciously) to blunt cortisol levels.

Many people do that reflexively, however, they reach for carbohydrate-rich foods to blunt their cortisol, because that’s indeed what it does. It blunts cortisol when you ingest high carbohydrate foods, in particular starchy foods.

In summary, Dr. Andrew Huberman, a neuroscientist at Stanford University, highlights the crucial role that cortisol plays in regulating the body’s energy levels, focus, immune system function, and inflammation regulation. He explains that cortisol is not inherently good or bad but rather its regulation is critical. Disruptions to the natural cortisol pattern can negatively impact overall health and wellbeing. Therefore, Dr. Huberman suggests various strategies to maintain a balanced circadian rhythm and cortisol pattern, including maintaining a consistent sleep-wake schedule, getting exposure to natural sunlight during the day, reducing stress, and avoiding exposure to blue light from electronic devices in the evening. Measuring and tracking cortisol levels can also help optimize health and wellbeing.Post navigation

The post Huberman on Biohacking your Cortisol appeared first on mTelehealth.

Reduce Inflammation

Inflammation is beneficial when the body requires it to combat acute infections or injuries. However, it becomes detrimental when it persists over a long period, leading to chronic inflammation. Chronic inflammation can speed up the process of aging[1]. So-called inflammaging contributes to premature frailty, wrinkles, and other physical symptoms of age, as well as earlier mortality.

Measuring is the First Step to Reducing Inflammation

Unlike acute inflammation, which manifests visibly as swelling, fever, or redness, the much more harmful low-grade chronic inflammation is hard to notice. You may feel symptoms such as exhaustion, unexplained weight gain, or aches, but in order to accurately assess the levels of chronic inflammation, it’s important to measure relevant biomarkers.

What is Inflammaging

The scientific community is still exploring whether inflammation is the main culprit behind aging or if aging itself triggers inflammation. However, what we do know for sure is that making healthy lifestyle choices and actively managing chronic inflammation can have a significant impact on our overall well-being. By adopting habits that regulate and lower inflammation, we can expect to enjoy a longer, more vibrant life with improved cognitive functions[2].

Inflammatory Factors

Chronic inflammation is caused by many modern lifestyle factors, including chronic stress[3], poor sleep, lack of exercise, environmental toxins, nutrient deficiencies[4], insulin resistance[5], and inflammatory foods (such as seed oils, conventionally processed meats[6], or MSG and food colorings[7]).

START YOUR JOURNEY

Which biomarkers are closely connected to inflammation?

Ferritin

Ferritin levels increase during inflammation to decrease the bacterial growth of iron, and as such it is a marker of both acute and chronic inflammation. High ferritin can be a strong predictor of many inflammatory diseases, including fatty liver disease [8] and many cancers.[9]

High Sensitivity CRP

C-reactive protein (CRP) is a protein produced by the liver that indicates inflammation in the body. A high-sensitivity CRP can detect even the smallest changes in inflammation, so it’s more useful for measuring low-grade inflammation.[10]

Homocysteine

Elevated homocysteine levels are linked to age-related inflammation and inflammatory diseases such as arthritis. [11] Homocysteine can be naturally lowered by consuming folate-rich foods, such as leafy green vegetables.[12]

Vitamin D

Low vitamin D levels are associated with chronic pain, mood issues, depression, fatigue, muscle weakness, high blood pressure, and susceptibility to frequent colds and the flu — all signs of inflammation. A recent study shows that vitamin D supplementation leads to a significant improvement in chronic inflammation.[12]

START YOUR JOURNEY

HERE’S THE DEAL

Why choose Dr. Miltie, Powered by SiPhox?

The lowest cost per biomarker testing, at-home sample collection,
interactive reports, and actionable insights.

At-Home Testing

No more driving to clinics. No more waiting in lines. The sample collection kit lets you collect your sample using only a few drops of blood.

Extremely Affordable

Blood testing is expensive. But it shouldn’t be. Meet Dr. Miltie, the lowest-cost per-biomarker test on the market.

Measure Progress

Users tell us that regular testing is key to reaching their goals. Whether you want to lose weight or have more energy—we have your back!

Actionable Insights

Personalized insights sets you up for success. Paired with your favorite wearables, our system creates insights to improve each biomarker.

COMPREHENSIVE TEST KIT

17 Included Biomarkers

Our at-home test kit contains the biomarkers you need to provide you with the best overall snapshot of your health.

Base

Cardiovascular Health

Hormonal & Nutritional Balance

Hormone+

Inflammation

Metabolic Fitness

TG:HDL Ratio

Vitamin D

Triglycerides

Total Cholesterol

TC:HDL Ratio

Testosterone:Cortisol

Testosterone

LDL

Insulin

Homocysteine

HDL

hs-CRP

ApoB:ApoA1

Cortisol

DHEA-S

Estradiol

Ferritin

TSH

FSH

HbA1c

ApoB

ApoA1

A FEW DROPS OF BLOOD

Is a few drops of blood really enough?

That’s right! A few drops of blood is all we need to test 17 biomarkers. Sounds too good to be true? Far from it…

Our sample collection card, the ADX100¹, is an alternative collection method, similar to an SST tube. Red blood cells are separated without a centrifuge, enabling the laboratory to perform tests on dry blood.

Are results accurate? Yes! We process samples in a 3rd party CLIA-certified lab. The test results have been cross-validated against standard finger prick and venous draws.

SELF SAMPLE-COLLECTION

Can I really collect my own sample?

Each kit contains a sample collection card, three adjustable lancets, band-aids, sterile gauze, an alcohol pad, and instructions.

Drawing your blood sounds scary at first. Especially if it’s your first time doing it. We’ve taken the time to make the instructions as easy to follow as possible.

Not only that, every customer can schedule a live one-on-one session with our certified phlebotomist for FREE (a person trained in collecting blood samples).

PERSONALIZED REPORTS

Ok, my results are in. What now?

This is the best part! After processing your sample, we create a complete report for each of your 17 biomarkers.

You can then access your reports from your personal reports dashboard. Each report comes with an easy-to-understand graph and personalized insights you can use to improve each biomarker.

The dashboard lets you connect your favorite wearables to make your reports even more insightful. Improved sleep and activity scores are highly correlated with improved hormonal balance and lower inflammation in our user base.

CORRELATE YOUR DATA

Include Your Wearable

Frequently Asked Questions

If your question is not found below, feel free to email us your question at: support@DrMiltie.com

Is the SiPhox Health blood test kit equivalent to standard labs?

How are you able to offer the lowest cost per biomarker in the industry?

Which biomarkers are being tested?

Why should I use a wearable with SiPhox Health?

What wearable devices are compatible with SiPhox Health?

How do I view my test results?

What makes SiPhox Health Reports unique?

Can I give my kit away as a gift?

I’m having trouble collecting enough blood for the test, what can I do?

I think I messed up my collection card. What do I do?

What is the Hormone+ Panel?

References

The post Why should you be tracking inflammation markers? appeared first on mTelehealth.

Sleep and Mental Health

Sleep plays a vital role in maintaining and promoting optimal mental health. As humans, we spend about one-third of our lives sleeping, and this seemingly passive state has profound effects on our cognitive, emotional, and psychological well-being. In recent years, research has increasingly highlighted the intricate relationship between sleep and mental health, emphasizing the significance of a good night’s rest in promoting overall emotional resilience, psychological stability, and overall well-being.

The Connection Between Mental and Physical Health

Mental and physical health are closely intertwined. Poor mental health can negatively impact physical well-being while maintaining good physical health can positively influence mental well-being. Chronic stress, anxiety, and depression can contribute to physical health issues, while a healthy lifestyle and food choices can improve mood and mental well-being. Recognizing this interconnection is vital for overall health and happiness.

Sleep and Mental Health Today

Only 1 in 3 Americans get enough sleep. In our current day, the importance of sleep in maintaining optimal mental health has gained increasing recognition. The fastpaced, technology-driven society we live in often promotes a 24/7 culture, leading to disrupted sleep patterns, insufficient rest, and chronic sleep deprivation. Understanding when and why our patterns are affected, and with it, our mental health, is critical to solving this problem.

START YOUR JOURNEY

Which biomarkers are closely connected to sleep and mental health?

High Sensitivity CRP

Studies have found that higher hs-CRP levels are associated with insomnia and a general lack of sleep.[2] It can also be linked to oversleeping.[3] If your hs-CRP levels are high, it could be an answer for over/under sleeping.

Cortisol

Higher cortisol levels have been thoroughly linked to sleep deprivation and lack of sleep quality.[4] It is the hormone in your body that regulates stress levels, so understanding your levels is critical in analyzing the stress in your life. Cortisol is extremely important to measuring sleep quality and mental health and is easily measured from a SiPhox Kit.

TSH

TSH, or thyroid stimulating hormone, has been found to be linked to mood swings and heightened risk of depression.[5] Lower levels are more indicative of depressive risk and mood swings.

Testosterone and Estrogen

Levels of testosterone in men and estrogen in women are indicative of mood swings and irritability, both of which play a central role in mental health. In men, low testosterone levels have been linked to low energy, risk of depression, and lack of sleep. Meanwhile, higher levels are indicative of irritability.[6] In women, estrogen regulates mood and stress, so lower levels have been linked to mood swings and other issues.[7]

START YOUR JOURNEY

HERE’S THE DEAL

Why choose Dr. Miltie, Powered by SiPhox?

The lowest cost per biomarker testing, at-home sample collection,
interactive reports, and actionable insights.

At-Home Testing

No more driving to clinics. No more waiting in lines. The sample collection kit lets you collect your sample using only a few drops of blood.

Extremely Affordable

Blood testing is expensive. But it shouldn’t be. Meet Dr. Miltie, the lowest-cost per-biomarker test on the market.

Measure Progress

Users tell us that regular testing is key to reaching their goals. Whether you want to lose weight or have more energy—we have your back!

Actionable Insights

Personalized insights sets you up for success. Paired with your favorite wearables, our system creates insights to improve each biomarker.

COMPREHENSIVE TEST KIT

17 Included Biomarkers

Our at-home test kit contains the biomarkers you need to provide you with the best overall snapshot of your health.

Base

Cardiovascular Health

Hormonal & Nutritional Balance

Hormone+

Inflammation

Metabolic Fitness

TG:HDL Ratio

Vitamin D

Triglycerides

Total Cholesterol

TC:HDL Ratio

Testosterone:Cortisol

Testosterone

LDL

Insulin

Homocysteine

HDL

hs-CRP

ApoB:ApoA1

Cortisol

DHEA-S

Estradiol

Ferritin

TSH

FSH

HbA1c

ApoB

ApoA1

A FEW DROPS OF BLOOD

Is a few drops of blood really enough?

That’s right! A few drops of blood is all we need to test 17 biomarkers. Sounds too good to be true? Far from it…

Our sample collection card, the ADX100¹, is an alternative collection method, similar to an SST tube. Red blood cells are separated without a centrifuge, enabling the laboratory to perform tests on dry blood.

Are results accurate? Yes! We process samples in a 3rd party CLIA-certified lab. The test results have been cross-validated against standard finger prick and venous draws.

SELF SAMPLE-COLLECTION

Can I really collect my own sample?

Each kit contains a sample collection card, three adjustable lancets, band-aids, sterile gauze, an alcohol pad, and instructions.

Drawing your blood sounds scary at first. Especially if it’s your first time doing it. We’ve taken the time to make the instructions as easy to follow as possible.

Not only that, every customer can schedule a live one-on-one session with our certified phlebotomist for FREE (a person trained in collecting blood samples).

PERSONALIZED REPORTS

Ok, my results are in. What now?

This is the best part! After processing your sample, we create a complete report for each of your 17 biomarkers.

You can then access your reports from your personal reports dashboard. Each report comes with an easy-to-understand graph and personalized insights you can use to improve each biomarker.

The dashboard lets you connect your favorite wearables to make your reports even more insightful. Improved sleep and activity scores are highly correlated with improved hormonal balance and lower inflammation in our user base.

CORRELATE YOUR DATA

Include Your Wearable

Frequently Asked Questions

If your question is not found below, feel free to email us your question at: support@DrMiltie.com

Is the SiPhox Health blood test kit equivalent to standard labs?

How are you able to offer the lowest cost per biomarker in the industry?

Which biomarkers are being tested?

Why should I use a wearable with SiPhox Health?

What wearable devices are compatible with SiPhox Health?

How do I view my test results?

What makes SiPhox Health Reports unique?

Can I give my kit away as a gift?

I’m having trouble collecting enough blood for the test, what can I do?

I think I messed up my collection card. What do I do?

What is the Hormone+ Panel?

References

The post How can tracking biomarkers help you improve or maintain sleep and mental health? appeared first on mTelehealth.