Page 7 Heart Failure Remote Monitoring Evidence From the Retrospective Evaluation of a Real World Remote Monitoring Program

referred into the program by their care provider. Patients with end-stage renal disease, on any
chemotherapeutic medication, or having had any organ transplant were excluded from participation.

We conducted a retrospective review of the remote monitoring database (RMDR) to identify participants
enrolled in the CCCP between Jan. 1, 2008, and Aug. 31, 2012. The RMDR is a secured database

housed within the Partners HealthCare firewall where connected health data are processed and stored.
From the RMDR, we also collected program information of participants. This information included
program start of care and end of care dates. The list of identified program participants was sent to the
Partners HealthCare’s Research Patient Data Repository (RPDR) to access participants’ full clinical data

and also to identify eligible match controls. The RPDR is a large clinical data registry that gathers
medical records from various hospital systems and stores them in a central location [10]. We identified
control patients, not participating in the CCCP but receiving care at MGH, with any heart failure-related
International Classification of Disease, Ninth Revision, Clinical Modification (ICD-9-CM) and with similar

CCCP eligibility requirements. We excluded CCCP patients whose enrollment date in the program was
before the year of interest (2008), without documented index hospital admission before CCCP
enrollment. We also excluded CCCP patients (and corresponding matched controls) that were enrolled in
the program for less than 1 week. Control patients (and corresponding CCCP patient) with incomplete

clinical data, those not meeting CCCP entry criteria, and those who died prior to the CCCP enrollment
date of corresponding CCCP match were also excluded from analyses.

pg. 7